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Immune responses to stroke: mechanisms, modulation, and therapeutic potential

Some people notice mild nausea or reduced appetite within the first few hours of their initial injection, but meaningful therapeutic effects such as sustained appetite reduction and early weight changes typically develop over the first four to eight weeks as the dose is gradually escalated

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Heffernan M, Summers RJ, Thorburn A, Ogru E, Gianello R, Jiang WJ, Ng FM